February 4, 2019

EpiQuest-B is a unique software, based on an algorithm developed by Aptum Biologics Ltd. The program finds in silico antigenic epitopes and defines their relative immunogenicity, thus allowing to quickly and cost-effectively pinpoint the sites of immune response (and f...

November 9, 2018

Specificity of antibody that will be used for research or diagnostics is of primary importance. Lately, most of antibodies are developed against a selected peptide epitope from the sequence of a protein. This raises the question: can the specificity of antibody prepare...

November 2, 2018

Epitopes for cytotoxic lymphocytes bind to MHC class I molecules, and, in the context of MHC, are specifically recognised by T-cell receptor. It is generally accepted that T-cell epitopes may be divided into strong, moderate and weak, depending on their ability to effe...

October 4, 2018

EpiQuest has received recently a valuable addition: a new matrix to predict areas containing CTL epitopes. This is our first matrix for mouse CTL epitopes, as all matrixes for EpiQuest-T it is MHC-allele specific, and this one is for the most widely used mouse model, m...

January 5, 2015

There are very few adjuvants, especially available for Research and Development, that can substantially change the cytotoxic immune response. Meanwhile, it is often very critical to know whether the reason for poor cytotoxic immune response is the vaccine itself or poo...

December 28, 2014

Not every antigen has the properties required for its optimal processing, presentation and effective immune response, therefore, various adjuvants are used to boost the antibody production. Most of them helps forming a depot of the antigen, and only some are involved i...

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New matrix for EpiQuest-T correctly predicts the "strength" of a CTL epitope

October 4, 2018

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