Programs included into EpiQuest Suite v4

Below is the overview of programs included into the newest version of EpiQuest suite in relation to tasks of the in silico analysis

YOU HAVE A

Protein Sequence

YOU WANT TO

Find antigenic domains in the sequence along with the analysis of other parameters

EpiQuest-B
EPIQUES-B 2020.png

Analyse a protein sequence for its complexity and uniqueness of various domains

EpiQuest-C

Find domains that are likely to be immunogenic when immune response is directed against a protein in its native state

EpiQuest-IM
EPIQUEST-AB 2020.png

Find hydrophobic and hydrophilic regions of the molecule using different algorithms

EpiQuest-H

Find domains that are likely to contain strong, functional CTL epitopes

EpiQuest-T
EPIQUES-T 2020.png

Find areas in the sequence statistically more prone to mutation in the absence of specific selective pressure

EpiQuest-M

Find sequences exposed at the surface of the native moleule based on its sequence

EpiQuest-A
ACCESS 2020.png

Analyse the aminoacid composition of the molecule, set of molecules of peptides

EpiStat
COMPLEXITY 2020.png
HYDRO 2020.png
MUTABILITY 2020.png
EPISTAT 2020.png
YOU HAVE A

Collection of Peptide Epitopes

YOU WANT TO

Rank peptide B-epitopes, selected by other means,  according to their antigenicity (ability to elicit strong humoral response)

B-Scanner
B-SCAN.png

Rank CTL epitopes, selected by other means, according to their antigenicity (ability to elicit strong CTL response)

T-Scanner
T-SCAN.png

Rank the pre-selected B or T epitopes according to their uniqueness (complexity)

C-Scanner
C-SCAN.png